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中文
在2号和3号外显子被一个含有lacZ和neo的 cassette替换，这个cassette是通过同源重组插入的。被删除区域编码了该蛋白的微管结合和束状化特性。 Western blot和免疫组化结果显示，杂合子雄性鼠的半个体中没有检测到蛋白，而杂合子雌性鼠中蛋白水平较低，这表明目标位点并未产生蛋白。lacZ基因的表达由内源性启动子驱动。(来源：J:78746)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
