基因的1-2外显子(732bp),编码前134个氨基酸的部分,被替换为连接到诺卡因抗性基因的人源CD2报告基因。对杂合突变动物脾脏RNA进行Northern blot分析,使用删除区域的探针未检测到基因转录本。(来源:J:71681)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
45

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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