通过体内表达Cre重组酶,从Stk11tm1Rdp基因的第3至6外显子被去除了。对来自纯合突变小鼠胚胎成纤维细胞的 Western blot 分析未检测到蛋白质。(来源:J:78818)
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Exons 3 through 6 were excised from Stk11tm1Rdp via the in vivo expression of cre recombinase. Protein was undetected by Western blot analysis of mouse embyronic fibroblasts derived from homozygous mutant mice. (J:78818)