将基因的5' DNase敏感位点1(HS1)替换为一个由诺福克病毒序列(loxP)标记的抗氨苄青霉素基因座,同时HS4-6区域替换为一个由loxP标记的抗羟氨苄青霉素基因座和部分诺福克序列的抗氨苄青霉素基因座,通过同源重组实现这一替换。(来源:J:60714)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129
Targeted
插入,基因内删除
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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