从8到11号外显子被插入了通过同源重组插入的诺姆西林选择座。通过在多种组织中进行 Western Blot 分析,对纯合突变小鼠的蛋白质检测未发现。(来源:J:60946, J:78491)
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Exons 8 through 11 were replaced with a neomycin selection cassette inserted via homologous recombination. Protein was undetected in homozygous mutant mice via Western blot analysis of various tissues. (J:60946, J:78491)