在内含子4的两侧各有一个loxP位点,5号和6号外显子由一个内含子6中的3'端loxP位点引导的neo cassette包围。转基因小鼠的基础血胆固醇和甘油三酯水平与野生型小鼠相似,这表明内含子中的neo cassette不影响基因表达。(来源:J:53390)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
2
9

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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