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中文
内源性基因通过一种构建被修饰，其中第217位由定点诱变改变为甘氨酸而非缬氨酸。目标位点（对应人类蛋白中的Val205）位于N指结构域，参与锌指蛋白的结合。随后在含替换突变的外显子内插入了floxed neo cassette。与携带Gata4tm1.1Sho基因突变小鼠比较，表明内含子中的neo cassette并未影响基因表达。（来源：J:77392）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
