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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Hydin
hy3-Tg(Bdnf)459Ove
Alias:
OVE459
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基础信息
表型特征
文献报道
将Bdnf编码的转录本随机插入到Hy3基因中。杂交实验表明,携带这种等位基因的 mice 与Hy3小鼠交配并未表现出补救作用,这表明这两处突变是等位的,并且很可能源自同一基因或一组基因功能的受损(来源:J:83437)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2386736
FVB/N
--
插入
隐性
1
2
3
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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