整个编码区域被一个包含lacZ和floxed tk-neo基因的载体替换。lacZ基因位于起始密码子下游。RNAse保护实验用于证实纯合突变小鼠中没有转录本。β-半乳糖苷酶的表达由内源性启动子驱动。(来源:J:78982)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入,基因内删除
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1
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14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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