将Cre重组酶连接到Fabp4启动子上,该启动子在白色和棕色脂肪组织中活性较高。Northern blot分析和功能试验表明,转基因在棕色和白色脂肪组织中表达丰富,而骨骼肌、肝脏和心脏等其他组织中未检测到显著表达。(来源:J:73557, J:88210)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count