Wnt1基因的启动子位于cre重组酶编码序列之前,cre重组酶序列后面跟着Wnt1增强子。Wnt1调控序列最初在中脑中指导表达。神经管闭合后,表达出现在中脑的背、腹中线,以及中脑-后脑连接处,还有背柱的脊髓区域。在基因的6425500-6456783位置插入了Line 11,导致31,283bp的缺失。Founder line x的拷贝数大于5。(J:69326)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x CBA/J)F1/J
--
插入,基因内删除
--
1
--
797

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部