经过在体表达Cre重组酶将敲除的neo cassette剔除后,细胞因子应答驱动区域和exon 1被留有一个单个的LoxP位点。通过分析脾脏中获取的树突状细胞,发现纯合突变小鼠中正常蛋白水平得到了检测。(来源:J:68147)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
--
18

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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