细胞因子应答驱动区域和exon 1被一个上游的单个loxP位点和下游的floxed neo cassette包裹。对脾脏树突状细胞的研究显示,与野生型小鼠相比,纯合突变小鼠中编码蛋白的水平降低了4到5倍。(来源:J:68147)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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