大部分基因通过同源重组,用含有5'非翻译区和634bp编码序列的2.2kb区域替换,被删除了。通过PCR基因型分析,我们观察到了到E9.5日的纯合突变胚胎。同位素标记并未在这些纯合突变胚胎中检测到基因表达。(来源:J:61449)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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