Cre重组酶在鼠CD4调控元件的驱动下表达。CD4增强子、启动子和沉默子共同在CD4+ T细胞发育的特定阶段驱动表达。转基因构建的整合位点位于染色体3的60,335,693-60,341,285位(qD),插入包含至少15个完整的转基因构建序列拷贝。(来源:J:73127, J:302838)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count