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中文
这个基因通过同源重组，用诺美霉素抗性基因 cassette 替换了一个包含第5和第6外显子的1kb区域，导致基因发生中断。目标突变导致编码赖氨酸zipper结构域的序列缺失，这是与肾素相互作用所必需的。杂合子突变动物的基因转录未在肾RNA的Northern blot分析中检测到。(来源：J:62268)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
