大多数编码基本 helix-loop-helix 区域的exon 2被一个包含IRES-lacZ和neo基因的 cassette 替换。对纯合突变胚胎的RT-PCR分析未检测到转录。β-galactosidase的弱表达,推测由于IRES效率不足,展现出与内源基因相似的表达模式。(来源:J:63415)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count