将小鼠Nr4a1的cDNA与小鼠Lck近端启动子连接后,用作转基因。对胸腺和胸腺细胞的Northern和Western印迹分析显示,转基因动物中RNA和蛋白质表达显著增加。此外,转基因胸腺细胞的核提取物在DNA结合活性上也明显强于野生型。(来源:J:78762)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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