将小鼠Nr4a1的cDNA与小鼠Lck近端启动子连接后,用作转基因。对胸腺和胸腺细胞的Northern和Western印迹分析显示,转基因动物中RNA和蛋白质表达显著增加。此外,转基因胸腺细胞的核提取物在DNA结合活性上也明显强于野生型。(来源:J:78762)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count