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中文
这个基因通过同源重组，用PGK-neo cassette替换了exons 1和2，导致前131个氨基酸缺失并产生下游框架移位。通过E14.5时的PCR基因型分析，我们检测到了纯合突变胚胎。来自E12.5纯合突变胚胎的鼠胚胎成纤维细胞的 Western blot结果显示没有蛋白质产物，这证实了基因的失活。（来源：J:61666）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
