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中文
Exon 1被替换为一个PGK-Hprt cassette，通过同源重组实现。靶向删除在纯合突变体动物中通过Southern blot分析得到了确认。脑组织切片的原位杂交证实了纯合突变体中基因表达的缺失。(来源：J:35874)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
