Mesp2基因的全长被同源重组的方式替换为一个内切Cre基因和一个PGK-puro载体,这个操作发生在含有突变Mesp1(Mesp1tm3Ysa)基因的ES细胞系中。Mesp2启动子驱动Cre重组酶的表达。(来源:J:62984)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
插入,基因内删除
--
1
5
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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