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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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基因编辑小鼠
Nrf1
tm1Rcs
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基础信息
表型特征
文献报道
从exon 2内部延伸到exon 4内的序列被替换成一个包含lacZ和neo基因的插件。删除区域编码了86到166的氨基酸,构成了核定位信号和DNA结合与二聚体化区域。β-半乳糖苷酶的表达被证实由内源性启动子驱动。(来源:J:67376)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2385947
129X1/SvJ
Targeted
插入,基因内删除
--
1
--
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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