这个基因的整个编码区域被替换为一个带lacZ序列的内切位点loxP标记的诺卡因选择元件,随后是Neo cassette。在产生嵌合小鼠之前,通过暂时的Cre表达,ES细胞中去除了诺卡因选择元件。对纯合小鼠大脑的RNA进行Northern blot分析显示,这个等位基因未检测到可识别的转录本。(来源:J:69606)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
2
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部