这种等位基因通过将增强绿色荧光蛋白(EGFP)序列替换了Hoxa2tm2Fmr中一段编码前72个氨基酸的exon 1部分,是由携带了germline中cre重组酶表达的实验鼠与Hoxa2tm1Ipc靶向区域缺失区域的鼠杂交产生的(J:75129)。在杂合突变胚胎中检测到的EGFP表达模式与内源基因的表达模式一致。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入
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1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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