人类APP基因,编码APP695.SWE突变(K670N和M671L)的过表达。构建中含有融合了hamster朊蛋白驱动序列的APP基因。通过免疫印迹在转基因小鼠大脑中测量APP表达(文献源:J:29880, J:80638)。
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count