在Srftm2Nor中,包含整个exon 1编码区域的floxed区域被广泛表达的Cre重组酶剪切掉了。剩下的是一段5'非编码区的floxed neo cassette,连接在exon 1的一部分上。(来源:J:75123)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
载体插入引起的破坏
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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