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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Tgfbr2
tm1.2Hlm
Alias:
Tgfbr2
E2flx
+Exon2/-Neo
r
TGFbetaRII
f
Tgfbr2
loxP
TbetaRII
flox
Tgfbr2
floxE2
Tbr2
fl
floxed-Tbr2
Tgfbr
floxE2
TbetaRII
flox+
TGFbeta IIR
fl
Tgfbr2
fl
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基础信息
表型特征
文献报道
这个等位基因来自Tgfbr2tm1Hlm。在单细胞阶段表达Cre重组酶导致了含neo转基因的含删除区域的剪切。剩下的两个单个LoxP位点位于exon 2的外侧。(来源:J:75073)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2384513
129S6/SvEvTac
Targeted
插入
--
1
11
191
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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