在exon 2的3'端,通过插入lacZ和neo序列的 cassette,删除了编码部分激酶区的区域。通过 Western blot 对纯合突变小鼠胚胎成纤维细胞的分析,证实了内源性基因座不产生这两种已知的isoform(来源:J:78190)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
--
43

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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