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在信号肽编码的外显子1位置，通过同源重组替换为抗氨苄青霉素抗性基因。Southern blot结果显示，几个靶向载体以串联方式整合在头尾相连的位置。用同源突变动物的周围神经蛋白进行 Western blot 检测，证实了基因表达的缺失。通过同源突变动物股神经切片的免疫组化分析，使用针对该蛋白的多克隆抗体，未检测到免疫反应性染色。(引用：J:3234)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
