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中文
在模仿DM20亚型的情况下，删除了105个碱基对的exon 3，然后在内含子3中插入了抗氨苄青霉素抗性基因座，以干扰基因产物的剪接。北半球印迹分析证实了纯合突变动物大脑中正常转录本的缺失。对纯合突变体的髓鞘样本进行 Western 印迹和银染色的SDS-PAGE电泳，未检测到PLP或DM20亚型的蛋白质产品。(来源：J:21976)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
