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中文
一段包含exon 1的0.9kb基因区域被替换成一个由loxP位点引导的诺卡因抗性基因座。在正确靶向的ES细胞中通过Cre重组酶的暂时表达移除了这个neo cassette。Northern blot结果显示，父源染色体上携带突变的动物基因表达显著降低，而母源染色体上的则没有显著变化。（来源：J:70275）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
