在Ppyr1基因下游插入了带有诺卡因抗性基因座的敲除载体,通过同源重组在内含子1中引入了第三个loxP位点。通过针对目标ES细胞的Southern blot分析,用Ppyr1编码区域的探针对突变等位基因进行了确认。(来源:J:76479)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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