在1号外显子(exon 1)从第119到第164位的序列被替换了 neoventa 选择标记。删除的区域包含起始翻译位点和前5个密码子。在E13.5胚胎的RNA酶保护实验中,检测到这个等位基因产生了异常转录物,但来自E13.5纯合胚胎提取物的 Western blot 上未发现信号。(来源:J:23139)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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