这个等位基因是由通过EIIa启动子驱动cre重组酶表达的转基因小鼠与携带Hnf4tm1Gonz基因的鼠杂交产生的。cre的表达导致了neo标记 cassette的剔除,留下包含4和5号染色体外区域的含floxed标记的区域。同时,Hnf4tm1.2Gonz也是通过相同的方法生成的。(来源:J:67396)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入
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1
11
68

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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