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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Gjb2
tm1Ugds
Alias:
Cx26
fl
Cx26
loxP
Gjb2
tm1Ptt
Cx26fl
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基础信息
表型特征
文献报道
在exon 2的编码区,通过1号内含子的loxP位点和插入到exon 2的敲除neo cassette,形成了一个被标记的基因。免疫荧光染色结果显示,这个敲除等位基因的表达模式与野生型无异。(来源:J:77823)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2183509
129P2/OlaHsd-Hprt1b-m3
Targeted
插入
--
1
27
39
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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