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插入了一个新霉素选择座，删除了包含近端启动子和34个密码子的1.6kb序列，包括起始的甲硫氨酸密码子。通过Northern blot分析来自大脑和脊髓的RNA，对纯合突变小鼠的转录未检测到。蛋白质缺失通过使用能检测到磷酸化或非磷酸化蛋白的多种抗体进行 Western blot 实验得到了确认。(来源：J:77654)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
