2.7千碱基的序列,包括5号外显子的一部分和6、7、8号所有外显子,被替换了 neoventa 选择标记。通过Northern blot和Western blot对不同组织进行分析,确认了纯合突变小鼠中没有转录物和蛋白质的存在。(来源:J:77647)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
插入,基因内删除
--
1
--
20

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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