这种等位基因赋予了对百日咳博德氏菌诱导的组胺过敏耐受性,存在于C3H/HeJ和CBA/J这两个菌株中。它们的预测蛋白序列中有三个一致的氨基酸变异(L263P、M313V和S331P),这些位于第三内膜环,被认为与信号传导功能有关。(来源:J:77938)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C3H/HeJ or CBA/J
Spontaneous
核苷酸替换
隐性
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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