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中文
在2、3和4号外显子插入了新霉素选择性 cassette 删除序列，该区域替换了参与MgATP结合的富含甘氨酸的motif。对纤维细胞提取物进行 Western blot 分析表明，纯合突变胚胎中目标等位基因产生的所有已知表型均缺失。来自纯合突变小鼠组织提取物的免疫沉淀在体外无法使GST-Cdc25C发生磷酸化，这表明激酶活性丧失。(来源：J:68830)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
