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中文
这个转基因表达了一种融合蛋白，由Cre重组酶和改造后能特异结合4-hydroxytamoxifen而不结合内源雌激素的雌激素受体的配体结合域组成。CAG启动子，结合了鸡β-actin驱动子/增强子以及CMV-IE增强子，能在大多数组织中驱动高表达。在添加Tamoxifen的情况下，融合蛋白能进入细胞核，Cre在那里能剪切条件性修饰基因的loxP标记片段。（来源：J:76130）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
