Log In|Sign Up
中文
一段2.5千碱基的基因，包括12-14号外显子，通过同源重组被替换为PGK-neo cassette。基因靶向事件导致了C末端的SH2结构和酪氨酸激酶域的ATP结合位点（氨基酸497-607）的缺失。通过Southern blot分析，我们识别出了纯合突变的胚胎干细胞。(来源：J:76509)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
