一种由β-actin驱动的FRT-flanked诺卡因抗性 cassette替换了特定于180 kDa蛋白亚型的exon 18。在纯合突变小鼠脑组织的免疫印迹分析中,新生儿和成年组织中未检测到180 kDa亚型,而在新生儿组织中检测到了140 kDa亚型,但成年组织中未检出。(来源:J:37891)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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