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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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基因编辑小鼠
Il6
tm1Mur
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基础信息
表型特征
文献报道
在大约95%的exon 4区域,替换了新米星抗性筛选元件。通过ELISA检测,无论是体外用LPS刺激的小鼠胸腺微环境细胞上清液,还是体内对LPS刺激动物血清,实验结果显示纯合突变小鼠中未检测到编码蛋白。(来源:J:25684)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2182222
129P2/OlaHsd
Targeted
插入,基因内删除
--
1
7
12
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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