在Neo小鼠中,插入了一个新霉素选择座,它删除了编码蛋白质核心区域大约80%的3到6号外显子。对总RNA进行Northern blot分析,使用针对目标区域的探针,结果显示这些转基因雄性小鼠的睾丸中没有转录本存在。(来源:J:69502)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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