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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Stat5b
tm1Hwd
Alias:
STAT5b
-
Stat5b KO
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基础信息
表型特征
文献报道
这个基因通过同源重组在第181位密码子插入了耐药性质粒,导致其功能受损。在纯合突变动物的肝脏、脾脏、乳腺、胸腺、肾脏和骨骼肌中,通过Northern和Western印迹分析证实了基因表达的缺失(来源:J:41784)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
2181592
Not Specified
Targeted
插入
--
1
4
31
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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