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中文
在基因的两个外显子周围引入了loxP位点，通过同源重组。携带了定向突变的实验鼠与HSP-cre敲除株杂交，导致了两个外显子和5'上游的一半CG岛被消除。通过Northern blot分析，证实了同卵突变胚胎卵黄囊中该基因表达的缺失。(来源：J:76871)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
