在某些isoforms中被剪切的Exon 6被删除,并被一个诺卡因选择标记 cassette 替换。来自纯合突变小鼠的细胞免疫荧光分析显示,B淋巴细胞中编码蛋白缺失,而周边T细胞的表达水平较低。对外周T细胞的流式细胞术分析确认,编码Exon 6区域的蛋白缺失,而Exon 5编码区域的蛋白以低水平存在。(来源:J:13163)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
插入,基因内删除
--
1
2
44

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部