Csf1r^tm1Ers

Exon 3 was disrupted by the insertion of an in-frame cassette containing a humanized green fluorescent protein sequence and a neomycin resistance gene. While annulment of the allele in mutant mice was indicated by Western blot analysis of bone-marrow derived macrophages, expression of the green fluorescent protein could not be detected by fluorescence microscopy or flow cytometry. (J:73663)