这种假基因是由Bmp4tm3Blh衍生而来的。在3号和4号外显子周围插入了LoxP位点,然后在LoxP插入点的3'端插入了无启动子的lacZ基因。最后,通过Flpe介导的重组,去除了lacZ基因下游的弗里特(Frt)标记的诺卡因选择 cassette。(来源:J:75136)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
插入
--
1
5
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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