拥有Ccr9tm1Mal基因突变的实验鼠与普遍表达Cre重组酶的鼠杂交,产生了缺失第3染色体段和插入了neo抗药性基因座的基因位点。RT-PCR分析和RNA酶保护实验结果显示,纯合突变小鼠胸腺组织中没有转录本存在。(来源:J:72386)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
基因内删除
--
1
--
15

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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